{"id":2745,"date":"2026-08-03T03:31:43","date_gmt":"2026-08-03T03:31:43","guid":{"rendered":"https:\/\/futureknowledge.in\/?p=2745"},"modified":"2026-08-03T03:31:43","modified_gmt":"2026-08-03T03:31:43","slug":"huwe1-targets-mitochondria-via-rmc1-to-promote-neurodevelopment","status":"publish","type":"post","link":"https:\/\/futureknowledge.in\/?p=2745","title":{"rendered":"HUWE1 targets mitochondria via RMC1 to promote neurodevelopment"},"content":{"rendered":"<p>Proceedings of the National Academy of Sciences, Volume 123, Issue 30, July 2026. &lt;br\/&gt;SignificanceMutations in HUWE1 are a recurrent cause of X-linked intellectual disability, yet most studies have focused on catalytic defects and the consequences for nuclear substrates. The present work identifies a mitochondrial pathway that is &#8230;<\/p>\n<p><em>Source: <a href='https:\/\/www.pnas.org\/doi\/abs\/10.1073\/pnas.2619864123?af=R' target='_blank'>Read the original article on www.pnas.org<\/a><\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Proceedings of the National Academy of Sciences, Volume 123, Issue 30, July 2026. &lt;br\/&gt;SignificanceMutations in HUWE1 are a recurrent cause of X-linked intellectual disability, yet most studies have focused on catalytic defects and the consequences for nuclear substrates. The present work identifies a mitochondrial pathway that is &#8230; Source: Read the original article on www.pnas.org<\/p>\n","protected":false},"author":1,"featured_media":2746,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[36,3],"tags":[12,28,32],"class_list":["post-2745","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-share-suggestions","category-technology","tag-impact-intc","tag-signal-buy","tag-stage-stage-1"],"_links":{"self":[{"href":"https:\/\/futureknowledge.in\/index.php?rest_route=\/wp\/v2\/posts\/2745","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/futureknowledge.in\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/futureknowledge.in\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/futureknowledge.in\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/futureknowledge.in\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2745"}],"version-history":[{"count":0,"href":"https:\/\/futureknowledge.in\/index.php?rest_route=\/wp\/v2\/posts\/2745\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/futureknowledge.in\/index.php?rest_route=\/wp\/v2\/media\/2746"}],"wp:attachment":[{"href":"https:\/\/futureknowledge.in\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2745"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/futureknowledge.in\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2745"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/futureknowledge.in\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2745"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}