Proceedings of the National Academy of Sciences, Volume 123, Issue 30, July 2026. <br/>SignificanceAntibiotic producers must be resistant to the toxins that they produce, but how such self-resistance develops is a mystery. The mycophenolic acid (MPA) biosynthetic gene cluster (BGC) encodes a resistant variant of the MPA target inosine …
Technology & Future Tech
An activity–resistance trade-off constrains enzyme evolution
Proceedings of the National Academy of Sciences, Volume 123, Issue 30, July 2026. <br/>SignificanceAntibiotic producers must be resistant to the toxins that they produce, but how such self-resistance develops is a mystery. The mycophenolic acid (MPA) biosynthetic gene cluster (BGC) encodes a resistant variant of the MPA target inosine … Source: Read the original article […]
