Structural and mechanistic basis for membrane recognition and activation of the vacuolar lipase Atg15

Proceedings of the National Academy of Sciences, Volume 123, Issue 30, July 2026. <br/>SignificanceMembrane turnover is fundamental for cellular homeostasis, yet how cells achieve preferential and safe degradation of internal membranes remains poorly understood. We reveal the structural and mechanistic principles governing the activation … Source: Read the original article on www.pnas.org